Get her spayed.

Unfortunately that's the only thing that'll really help Cats are seasonally polyestrous, which basically means once they go in heat, they will have continual heats until they are either mated or spayed, or the daylight cycles change again. But this can go on for sometimes up to a year.

I would book her an appointment asap and make sure she's on lockdown in the meantime. You could try something like rescue remedy, but I'm not sure how much it would help.

 

We have an appointment but she beat us to it. She just seems miserable and I was seeing if there is anything I can do to relieve the symptoms.

 

Miserable? LOL. She's probably just... Aroused. Those yowls are to attract males, not a pain response.

However, if you are concerned that there might be something else going on... It can't hurt to talk to your vet about it. Especially if this is the first estrus you've dealt with and aren't familiar with what to expect.

 

Well, I sort of got the impression that by miserable she means frustrated from the....well, lack of action LOL.