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Discussion Starter · #1 ·
(link to full article w/charts and stuff)

Dog behavioral problems can manifest themselves in many ways. From soiling in the house to displaying aggression against people and other dogs. Owner’s who love these dog’s spend millions(maybe billions) on training and management to try and alleviate the problematic behaviors. But a study published last month in the journal Applied Animal Behaviour Science has reached a startling conclusion that may change the playing field dramatically. Antioxidant supplementation may be the “magic bullet” to fix problem behavior, where everything else has failed.


The chart on the left defines the problem behaviors that were used in the recruiting criteria for the study. These specific problems contribute to a startling statistic, up to 20% of all owner surrenders in the United States are due to the dogs behavioral problems. That translates to around 780,000 dogs every year relinquished to shelters due to problematic behaviors.


The researchers focused on the serum trace elements Zinc, copper, and Iron–each with major implications for overall healthy brain function– along with a measure of total antioxidant capacity. They recruited a group of 30 “terrier” dogs(more on this in my conclusion) that were split into two groups–14 without behavioral issues and 16 with at least one behavioral problem in common–

The goal of the study was to compare the serum trace elements and total antioxidant levels in these two groups to assess any statistically significant differences. The researchers use blood samples to measure each dog’s trace element levels. While iron and copper levels showed no statistical correlation, Zinc and total antioxidant capacity(TAC) levels were significantly lower for dogs with behavioral problems. It is also worth noting that there was no significant difference in these levels(zinc and TAC) between dogs with only 1 behavioral issue and those with many.



These results are inline with other studies focusing on zinc levels. A plethora of research on humans has shown zinc to be crucial to proper neurological function as it affects neurotransmitter responses and therefore has a direct link to the brain’s chemistry. Another study cited by the authors showed that zinc-deficient mice displayed higher levels of aggression than their normal counterparts. Given this information, it is not surprising to find that the authors conclude “The present research is the first study in which a number of trace elements and antioxidants were evaluated in terrier dogs with behavioral problems. The results of the present study revealed lower levels of serum zinc and total antioxidant capacity in terrier dogs with behavioral problems. These findings support the hypothesis that using food supplements containing antioxidants and zinc could be beneficial to prevent or improve behavioral problems in dogs”

Discussion

As I was reading through this study, the sample size immediately stood out to me as being very small, but the researchers to address this problem, pointing out that in a larger sample size they believe that the results of the Iron/copper tests would start to show a statistical correlation with behavioral issues as well. The other issue that struck me as odd is that the authors only identify the dogs as “terriers”. There is a large spectrum of terrier breeds. Everything from rat terriers to American Pit Bull Terriers. There is no mention of the specific breeds of dogs involved anywhere in the study. I’m uncertain as to the reasoning behind this, but I’m looking forward to hearing your thoughts on the subject.

This is exciting research without a doubt. I’m looking forward to following where it leads us in the future.
 

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....So why are dogs suffering from antioxidant depletion? It brings us back to the elephant in the room, over vaccination, because many of the ingredients in vaccines cause this very issue. For example, thimerosal (mercury) which is is in almost every single rabies vaccine, the exception being two, one has trace amounts and the other is thimerosal-free but contains aluminum. Aluminum also a very common ingredient in vaccines as it is used as an adjuvant to elicit an immune response to the antigen.

It has been demonstrated that chronic aluminum exposure in rats induces depletion of glutathione in the liver as well as a significant reduction in the synthesis of bile acids.
http://people.csail.mit.edu/seneff/Entropy/entropy-14-02227.pdf

The autism community has long known about the issue of antioxidants and glutathione and glutathione deficits in autistic children.
 

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The operative word there is chronic, small doses at yearly intervals do not count as chronic exposure.

And autism is a spectrum disorder with no singular cause, the link found between autism and vaccines was retracted years ago, the scientist has been sued for organizing the study with a pharmasutical companies bribe and further rigorous studies have found no evidence for it. The guy walked into a hospital and looked at 11 children who had been brought to the hospital be evaluated for behavioral issues, they happened to get mmr on the way in. Talk about bad science.
 

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I just tried to edit that to remove it, sorry, not trying to create an off-topic argument. I think it's obvious this is a subject that I feel strongly about and I think Gnostic does too. Agree to disagree and leave it at that?
 

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The operative word there is chronic, small doses at yearly intervals do not count as chronic exposure.

And autism is a spectrum disorder with no singular cause, the link found between autism and vaccines was retracted years ago, the scientist has been sued for organizing the study with a pharmasutical companies bribe and further rigorous studies have found no evidence for it. The guy walked into a hospital and looked at 11 children who had been brought to the hospital be evaluated for behavioral issues, they happened to get mmr on the way in. Talk about bad science.
No, the case study you are referencing never said vaccines (actually it was specifically the MMR), caused autism, this is just parroting of what was written in the media, and there have been studies that replicate the finding of a "novel bowel disease" in autistic children following the MMR. You are also parroting garbage about Dr Wakefield, which shows you have done no independent research on the topic, I have been a vaccine researcher for over 20 years, so I know my stuff. Also, you are probably not aware that a CDC whistleblower, named William Thompson, admitted in 2014 that a study he and CDC colleagues published in 2002 (I think) was fraudulent and hid a 3 fold increase in autism following the MMR vaccination in African American boys below the age of three.

Will CDC Whistleblower on Vaccines Testify Before Congress?

You are clearly not aware that Dr Wakefield assembled a team of highly qualified research doctors to work on the case studies, including the world's leading pediatric gastroenterologist Dr John Walker-Smith, who was exonerated of all charges (same charges Dr Wakefield was struck off for) because his insurance was willing to pay for the appeal. It was not bad science, it was in fact, good science.

Yes, I feel strongly about this topic and I have the knowledge to back up what I write, I don't just parrot media/pharma talking points.
 

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Discussion Starter · #11 ·
@sullyrules interesting study. Do you know if there are any plans to implement the results in a randomized trial for supplements?
The authors mention that this is just a first step in contuining research. I think they want to do a larger scale study to get a better handle on how the serum levels correlate to behavior problems, then, I would think, a randomized trial would be the next logical step.

It really bothers me that they only identify the dogs as terriers though. Like REALLY bothers me lol
 

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Excellent, hopefully they get the grants to do that.

I would be nice to know the breed criteria. I suspect they mean APBT and mixes, so they can reduce a variable, but considering how badly labeled they are they could be pulling lab mixes, right?
 
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