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Discussion Starter #1
Has anyone experienced a sudden personality change in their dog after giving them Sentinel Flavor Tabs? I have a new Red Heeler puppy, 7 months old, and have given her Sentinel three times. The first two she seemed fine, but within 24 hours of her last dose, it seems as if her personality and behavior changed. The next day she wouldn't leave the house and she would just lay on the bed and wouldn't eat. Now she's eating but before the pill she was always ready to play outside and now she seems scared of the slightest thing, cars, wind, noises. If she does start to play outside now she stops suddenly, looks around and quivers and runs back to the house. She won't even go outside to pee sometimes and if I carry her outside she'll just sit on the ground by the door and want to go back inside. It seems odd that it happened right after I gave her the tablet. This has been going on for the last few days now and she doesn't seem to be snapping out of it. What happened to the free running happy girl who wanted to play outside all the time? She seems so different now and I'm concerned. I'm now scared of these pills but I know she needs worm protection. I searched online and found only a few instances where others were asking the same question. So, I don't know if it's related or not, but I was hoping someone could help me out here. Thank you, I want my girl back!
 

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Discussion Starter #4
That's interesting, I've never heard of that. Could be. It was so sudden and came on within 24 hours of the pill so that made me wonder. I can only hope it is a fear stage. I will keep it in mind, thank you.
 

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Discussion Starter #5
I will definitely bring her in if it persists, thank you. It's just so strange. Right now I had this experience where she seemed excited to go outside and I thought that she was feeling better, we got outside, and within seconds she stopped and sat down and then ran back to the house. It's like she's suddenly afraid to cross the street or leave the yard. We live in the middle of nowhere, so it's all nature here. Not much to be afraid of, except the wind maybe. And this a girl who normally keeps me outside playing for hours.
 

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She could have had a bad reaction to the pills. Just another reason I don't give that kind of stuff to my dogs. Other than bringing home puppies I've never had a worm issue, rarely do fleas or ticks bother my guys and they get heartworm checked yearly. If they did pick up worms I'd get them treated. I've only had to use topical flea prevention a few times over the years. IMO I'd rather treat as needed than put poison on my pets every month. I know others will disagree with me and that is fine. Just so you know there are other ways.

I'd probably call a vet and see what they suggest.
 

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Discussion Starter #7
Thank you, I was not aware there was any other way. It's been a very long time since I've had a dog. The vet said it was part of what to do. I researched it before I gave it to her and almost didn't. I told the vet my concerns and she brushed them aside and said it was totally safe. Is it really ok to just get her checked for worms once a year?
 

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If it has something to do with a fear stage, it's still important to get it sorted out as fear imprints at these times and can linger for the dog's life. It's one of the reasons positive socialization is pushed constantly.

I agree with the others it's time to consult a vet.
 

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Any medication can have side effects, sometimes serious. What you describe is similar to the side effects Samantha had after taking nexgard, and as I recall it only occurred after the second or third dose. She also suffered neurological side effects from trifexis, could barley walk, very limited control of her back legs. She is now on frontline for fleas and heartgard for heartworm, but no side effects. Between the nexgard and a reaction to an injected antibiotic, for bronchitis, it took her almost a year to get back to normal. We had to take her to an internist, as our GP Vet felt he was out of his league, but she did recover and is great today.
 

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Thank you, I was not aware there was any other way. It's been a very long time since I've had a dog. The vet said it was part of what to do. I researched it before I gave it to her and almost didn't. I told the vet my concerns and she brushed them aside and said it was totally safe. Is it really ok to just get her checked for worms once a year?
There are many ways to deal with these things. Not everyone agrees and that goes for vets too. Traditional vets really push these things, and they are not 100% safe.There are possible side effects, plus whatever damage the poisons do over time to your dog's body. More holistic and homeopathic vets don't push monthly preventatives. My vet is holistic and they recommend testing over using these things all the time. Most worms are not a problem. Of course there are some situations where a dog is more likely to pick them up. My guys have never picked up worms. They are raw fed, including wild game when I can get it and we do take walks in the woods. I do use a bug spray I make up for when we go out to the woods and it works well, I use it too. It's just a mix of some essential oils and water. Sometimes vinegar in place of the water. For heartworm there is a particular time they can be transmitted. The temps need to be above 57*F for the heartworm to develop in the mosquito. The heartworm preventative is poison, a low dose to kill any heartworm that may be transmitted to your dog. A healthy dogs' immune system can kill off the heartworm before they can develop. If you check once or twice a year you can easily kill off any heartworms you dog may have. Where you live does play a part too, heartworm is much more common in the south where it is warm much of the year. I'd test more often, two or even three times a year. As far as intestinal worms go you can also test yearly or more if you'd like. It's as easy as dropping off a stool sample to your vet to look at.

As I said, all these things are poisons. I'm concerned what the long term damage is. I am not against using them as needed, they have their place.
 

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Discussion Starter #11 (Edited)
Thank you, I didn't realize that about the fear stage. I'm trying not to push her and be very gentle. The thing is she will play inside like normal but it's the outside that she's suddenly scared of. Like overnight. I can't get to the vet until next week, but will. The ingredient in Heartgard scares me, too, it was one reason I thought this one might be better. That one seemed to have some real adverse effects on Australian types. I feel at a real loss at what to do. The vet said that I should use this one because it guards agains whipworm which is in our area and she had when I got her. How can I make sure she stays worm free and non toxic? Oh, I see the post above now, sorry, must have posted while I was writing. Thank you!
 

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One thought; what has the weather been like? Some drugs can have light sensitivity as a side effect... It's not listed on the drug insert but it may be very rare/not considered serious enough/difficult to identify in dogs.
 

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Discussion Starter #13
It did just really cold and snowy at the same time, but she usually loves the snow.
 

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I would call the vet and let them know what's going on before bringing her in. I don't think a physical exam would tell the vet anything. If they think an exam is warranted, they will tell you.
 

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You say she is new but has gotten Sentinel three times already. Have you had her for three months? Sentinel is mainly used to prevent heartworms with an added bonus of killing other worms. It's not used as a dewormer per se. If she has been getting the Sentinel more often than once a month, she may be having a reaction to it. Even though Australian Cattle Dogs aren't high on the list of drug sensitivity to ivermectin drugs, you may want to have her checked to make sure.

Washington State University VCPL - MDR1 Test
 

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Discussion Starter #20 (Edited)
Thank you, I started the Sentinel again because it seemed as if it was going to be an early Spring. I admittedly am quite a novice about all this and thought I needed to start this early. Apparently I have a much smaller window in which it might be needed. I gave one to her on March 1st and then one on April 1st. The other dose she had was in December, as it was still so warm then. I figured she was handling it well so it wouldn't be a problem. Ugh. I wish I never gave it to her. She is still so afraid of going outside and this morning she won't eat her breakfast and won't even play indoors. She just runs back to her bed, ears down. Last night she seemed fine suddenly, playing indoors and even a little outside, and this morning it seems to have come back, even worse. She just seems so fearful of all these things that she used to love. I don't want to push her but she is going to need to go outside at some point to pee and poop. She has held it in for almost 12 hours now and I know she has to go, but she won't go outside. Granted, there is a bit of a snowstorm at the moment, but she never minded that before. It's like she starts to play or go outside, but then she gets this looks of panic and runs upstairs.

And, I did read about the ivermectin problem, I chose Sentinel because it doesn't use that ingredient. I didn't know they might be affected by milbemycin. I know that heart worms are not a big worry yet, but I guess I thought I needed to give it to her now because of the other worms it might prevent. I should get her tested anyway, just to find out. Thank you for your help. I can only hope that this wears off and she bounces back. I also don't want her associating me with making her do anything that causes fear. That is also a big concern. I'm trying to be gentle and to let her know that I am there for her.
 
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