I'm going to list various OTC calmatives i know & love - anyone who has a favorite, please jump in & add it.
All contributions happily accepted. Qs, observations, suggestions, past experiences, disasters...
I'll start with D.A.P. / Dog Appeasing Pheromone.
D.A.P. [ComfortZone for Dogs, Adaptil in the UK] is an especially good calmative; the pump-spray is extremely handy - carry it anywhere, use it as needed.
DAP goes on objects, not the dog; anything washable is fair game - so are waterproof finishes.
Don't use it on antiques, dry-clean only / Spot-clean only, garment leather, suede, or collectibles - otherwise, if in doubt, spray somewhere it won't show, wait 24-hrs, & check for discoloration, faded or running dye, etc.
Leather upholstery should be fine; i've not had any marks left by DAP, but that's not a warranty. If it's a $2K sofa-suite, TEST it. // Obviously, an antique silk or veg-dyed hand-woven wool rug wouldn't be a good risk.
DAP is a synthetic mimic of the pheromone produced by nursing Fs; it serves to calm pups so they make the most of nursing opps when Mom-dog returns, vs waste time whinging & fussing. // It lowers BP, pulse, resp, & secretion of cortisol & other stress hormones. It's a hard-wired response - no learning needed.
1 spritz is a measured application, & lasts about 90-minutes; it can be refreshed ad lib, no interactions / no dosage concerns.
I put it on collars [remove collar, spray 1 side 1x, opp side 1x, replace collar], anywhere the dog likes to lie [dog's bed, a chair, the corner of the sofa, a particular spot on wall-to-wall...], the car-seat & seat-belt harness, the LATCH / swing side of the crate door, crate door-sill, the leash a hands-length from the clip so that each time it swings past the dog's nose they get a whiff...
in the fold of a stuffed-toy, on a chew-toy in a crevice, on the exit door below the doorknob / dog's head-ht, etc.
I put it on my clothing:
the cuff of long sleeves, my gloves in cold weather, coat or jacket-cuffs, at knee-ht & ankle-ht on the outside seam of my pants, on my boots or shoes [dogs love to sniff shoes; they are rich in info about us, & where we've been].
I wear DAP when i enter the house of a dog who's reactive or turfy -
by putting it on shoes or boots / pants seams 2X / coat cuffs, & putting my HANDS in my pockets, avoiding eye-to-eye contact, i'm pretty sure i've saved myself a few bites from snappy dogs when owners weren't home, & i arrived to walk them / take them to the vet / feed them / change bandages, etc.
If it was a perfume, it would be my signature scent - Alas, it has no odor.