Have some experience with a dog with kidney disease. Ours has chronic renal failure and has for over a year now. We take her to the Vets weekly for fluid treatment for her kidneys. While that will not cure the disease, at least in our case it has stabilized her kidneys, numbers have been the same for over four months, and maybe a bit improved, even. Also her liver numbers were very high, probably due to, or at least contributed to by the phenobarbital she takes twice daily, because she has had seizures. So she has been on a liver supplement too, and her liver numbers have improved also since we have had her on the supplement. She also has had pancreatitis flares, so we have to watch her fat intake to control that too, in addition to a neurological auto-immune disorder, which she has had for the past four + years. For that she is on a maintenance dosage of prednisone, since trying to get her off that completely, resulted in a relapse. We try to get her to eat the low protein kidney friendly food, but she is not that fond of it, plus its high fat, bad for her pancreas, so its really a balancing act. She will be fourteen in January, so she is by no means a young dog, but, despite all her medical problems and medications etc, she is still enjoying a good quality of life, and is interested in everything around her. As long as that quality of life is good, we will continue to treat and medicate her.