That is so true. I could never expect to replace a dog or any animal. They were special for who they were. They will always be alive in my heart and mind.I've not seen it. I've heard of people cloning their horse too. It will be interesting to see the future reports, however unless you can duplicate the exact experiences and environment, it won't be the same dog. Same mental and physical capacities, I suppose, but learned behaviors and reactions to experiences and environment help mold a dog.
I almost feel sorry for the new pup with the added "expectations" to become the former dog, ya know?
Actually, that's a great question and I don't know for sure. I'd hope so if they were doing this for pets. That would be a reason I wouldn't do it (again, assuming I had zillions of dollars to waste... **sigh**)Do they still have the telomere problem with clones? Dolly, the original cloned sheep, aged 5x faster than normal due to short telomeres caused by the cloning process. I was unaware they had fixed that problem.
And, to top it off, the cloned animal can be vastly different from the original:Cloned animals that do survive tend to be much bigger at birth than their natural counterparts. Scientists call this "Large Offspring Syndrome" (LOS). Clones with LOS have abnormally large organs. This can lead to breathing, blood flow and other problems.
Because LOS doesn't always occur, scientists cannot reliably predict whether it will happen in any given clone. Also, some clones without LOS have developed kidney or brain malformations and impaired immune systems, which can cause problems later in life.
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When scientists looked at the telomere lengths of cloned animals, they found no clear answers. Chromosomes from cloned cattle or mice had longer telomeres than normal. These cells showed other signs of youth and seemed to have an extended lifespan compared with cells from a naturally conceived cow. On the other hand, Dolly the sheep's chromosomes had shorter telomere lengths than normal. This means that Dolly's cells were aging faster than the cells from a normal sheep.
To date, scientists aren't sure why cloned animals show differences in telomere length.
In a naturally-created embryo, the DNA is programmed to express a certain set of genes. Later on, as the embryonic cells begin to differentiate, the program changes. For every type of differentiated cell - skin, blood, bone or nerve, for example - this program is different.
In cloning, the transferred nucleus doesn't have the same program as a natural embryo. It is up to the scientist to reprogram the nucleus, like teaching an old dog new tricks. Complete reprogramming is needed for normal or near-normal development. Incomplete programming will cause the embryo to develop abnormally or fail.
IIRC, small white bits can be caused by incomplete pigmentation migration instead of genetics.A famous barrel racer had a somewhat plain little gelding that won 11 world championships .. her horse was a gelding, so could not breed. She cloned him so she could breed the clone. Granted, the breed association doesn't recognize him ..
Her original horse had no white on him at all .. solid bay. The clone had a blaze and two back stockings.. Looks nothing like the original ..