This is for informational purposes only. It is general info from the FDA. I have a degree in neuropharmacology but I AM NOT a physician nor vet. Please DO NOT take this as giving advice.
Phenylpropanolamine is a decongestant used for things like allergies to treat symptoms of nasal and chest congestion. It is also used in some diet aids, therefore it is also a sort of stimulant. And yes, it is used illicitly to make a kind of cheap speed.
As for ibuprofen (Advil, Motrin, etc) it is a Nonsteroidal anti-inflamatory drug. It reduces swelling by blocking certain chemicals (enzymes) that cause inflamation. It also blocks enzymes that are used in the body to control normal gastrointestinal and kidney function. Ibuprofen is absorbed very quickly into the bloodstream.
But in dogs, the drug is recycled over and over in the dog's body by way of the liver instead of being removed from the body by being metabolized (broken down) in the liver, then excreted through the urine or feces. the end result is the repeated exposure to the drug and is the cause of the poisoning effect.
The urinary incontinence (peeing uncontrollably is due to the effect it has on the kidneys Other things to watch for are dark, tarry stools, decreased appetite, vomiting, diarrhea, and bloody stools.
Treatment depends on how soon the treatment for poisoning is started. According to the VCA Animal Hospital, AKA, FDA, and Poison Control, treatment usually involves getting the drug out of the GI tract as soon as possible and administering activated charcoal. This was the protocol used when my Riley was attempting to soothe an upset stomach and took a BIG bite of an azalea bush. The VCA Hospital also uses an anti-vomiting medication and meds to protect the stomach and GI tract to reduce the bleeding. In my particular situation, a physician had me taking ibuprofen 4 times per day at 200MG per dose. I only took it for about 2 weeks, but it was enough that it caused Acute Bleeding Gastritis. Now I cannot take any kind of NSAIDs because I could end up with severe stomach bleeding. I am taking a medication to reduce the acid secretions in my stomach. The vet would possibly use the same type of drug that is appropriate for dogs.
If it were me, I would get your pup to an animal ER and/or find a competent veterinarian. What I did in finding a good vet was Googling independent reviews of several vets and asked around with friends and other members at my church. I found a very good one that way. Apps like Yelp, Quora, Yellow Pages were helpful.
These are only MY thoughts on it and what I have done relative to my dog only. But if it were me, I would act quickly in getting treatment for your pup.
I trust I did not overstep any boundaries here, but I felt like I should provide information to give you an overview of the problem. Again, this is not advice, just info and what I have done and would do.
My prayers are with you.
