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Possible allergic reaction to vaccines

This is a discussion on Possible allergic reaction to vaccines within the Dog Health forums, part of the Keeping and Caring for Dogs category; I should add that it is only the rabies vac that she is reactive too. Her DHPPC was given in the neck with no reaction ...

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Old 04-10-2016, 03:42 PM
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I should add that it is only the rabies vac that she is reactive too.
Her DHPPC was given in the neck with no reaction (was given at an earlier date)..........I intend to titer this year for these.......
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Old 04-10-2016, 04:40 PM
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Thanks for the feedback everyone!

When she goes back for her boosters I will definitely get the lepto separately. It's highly recommended to get here in Vancouver, BC because it rains A LOT here.

My puppy was pretty much back to normal within 48 hours.
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Old 04-15-2016, 11:57 PM
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Update: a week later the bump hasn't fully disappeared. Instead it's about th size of a loonie (Canadian $1 coin for the American members on here lol) and it's hard

It's uncomfortable for Mia when I touch it. Vet recommended to remove it so she's going under the knife tmw. Poor girl is going to have to wear the cone for 7-10 days I'm going to feel so bad leaving her at home when I go back to work on Monday.
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Old 04-16-2016, 11:52 PM
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Update #2: vet called and turns out the lump got embedded into her leg muscle so he's really glad he got it out as soon as we did. They're going to send it in to find out what happened and if it was an allergic reaction.

Hope this has never happened to any of you guys, so scary!
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Old 04-17-2016, 07:31 AM
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@LuvMyFluff:
I have personally only ever seen the vasculitis type reaction to one particular brand of Rabies vaccine (Fort Dodge). This type of reaction can often be avoided by giving the vaccine IM rather than SQ. Another option is, of course, to choose a different brand of vaccine; although no guarantee that a similar type reaction won't occur, it may be a good idea to avoid the previous offender.

@Yosiposhi:
Hopefully it will turn out to be simply inflammation, but always better safe than sorry. Hope Mia will be feeling better soon
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Old 04-17-2016, 09:38 AM
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Originally Posted by yoshiposhi View Post
Update #2: vet called and turns out the lump got embedded into her leg muscle so he's really glad he got it out as soon as we did. They're going to send it in to find out what happened and if it was an allergic reaction.

Hope this has never happened to any of you guys, so scary!

This kind of reaction is caused by the aluminum hydroxide (salts) which is used as an adjuvant in vaccines (an adjuvant causes an immune response). Lumps at the injection site is a common side-effect in human vaccines too. Basically, it is an immune response at the injection site to the aluminum. In the future, I would be very cautious about your dog receiving vaccines that use aluminum in them and would ask your vet to check the ingredients list and go with a different brand if necessary.
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Old 04-17-2016, 02:28 PM
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This kind of reaction is caused by the aluminum hydroxide (salts) which is used as an adjuvant in vaccines (an adjuvant causes an immune response). Lumps at the injection site is a common side-effect in human vaccines too. Basically, it is an immune response at the injection site to the aluminum. In the future, I would be very cautious about your dog receiving vaccines that use aluminum in them and would ask your vet to check the ingredients list and go with a different brand if necessary.
Oh wow thank you for this information! I had no idea! I will def check with them when she gets her boosters at 1year of age. Thank you!
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Old 04-17-2016, 03:17 PM
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[QUOTE=MdDVM;3001913]@LuvMyFluff:
I have personally only ever seen the vasculitis type reaction to one particular brand of Rabies vaccine (Fort Dodge). This type of reaction can often be avoided by giving the vaccine IM rather than SQ. Another option is, of course, to choose a different brand of vaccine; although no guarantee that a similar type reaction won't occur, it may be a good idea to avoid the previous offender.


@MdDVM
Looked at my rabies receipt and they used Nobivac3 and it was IM as she has no loose skin in that area, it is all muscle.......I'll ask if they have a dif manufacturer..............Thanks!
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Old 04-17-2016, 06:36 PM
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Oh wow thank you for this information! I had no idea! I will def check with them when she gets her boosters at 1year of age. Thank you!
You're welcome! If you are forced to vaccinate with an aluminum-containing vaccine because there are no aluminum-free options, then I recommend you bring a cold pack with you to the next vaccine visit and immediately put it on the injection site after the vaccine has been administered, this will help mitigate the immune response. You can keep putting a cold pack on the injection site for the next day or so following vaccination.
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