Multiple Skin Mast Cell Tumors and Treatment/Prognosis no surgery

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Multiple Skin Mast Cell Tumors and Treatment/Prognosis no surgery

This is a discussion on Multiple Skin Mast Cell Tumors and Treatment/Prognosis no surgery within the Dog Health forums, part of the Keeping and Caring for Dogs category; Hi Everyone, I am new to the forum and am hoping to get some information or insight on the dreaded mast cell tumor. I sadly ...

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Old 10-27-2017, 11:36 AM
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Multiple Skin Mast Cell Tumors and Treatment/Prognosis no surgery

Hi Everyone,

I am new to the forum and am hoping to get some information or insight on the dreaded mast cell tumor. I sadly have dealt with this awful cancer more than once with my dogs. First, my Baby Tank developed a tumor on his spleen back in 2010. We had it removed and went through some rounds of chemo even though we knew it would eventually kill him, but we got another really good 9 months and many more memories. He was sonly 8 when he passed away. Fast forward to 2015, Dozer (who was 4 at the time) developed a mast cell tumor on his ear, Grade II - Stage I. The majority of his ear was removed and we proceeded with chemo just to be on the safe side. Two years went by with no skin growths or health issues at all. Happy healthy pup. Three weeks ago I noticed two really small bumps on his side. Thought they might be bug bites because we camp and go hiking a lot. Within a matter of days there was more than 12 all over his body. We took him in right away and they biopsied the largest one. Vet said it was fine. Two weeks later he has 25+, ranging in size from a tic-tac to as big as quarters down his sides, neck and legs. I was so overwhelmed. I check him regularly because I know the reoccurrence is high but these came up so fast and I swear some overnight. We rushed him back to the vet and they removed the 3 biggest ones and sent them out for STAT testing. Just got the results back yesterday and they were not good. Due to the number of them he has, the vet does not know if they can be removed. He would literally be covered in scars and stiches. Vet recommended getting into see a specialist ASAP. I called over 15 different oncologist yesterday within 150 mile radius from our house and finally was able to get him an appointment for this coming Monday morning.

His blood work came back good at his normal vet and he has been acting like himself 100% so I am hoping that nothing has metastasized internally and this is all just on the skin. I know they will be able to determine that Monday but the three day wait is killing me and I have not been able to find any similar stories with so many tumors developing so quickly. I am hoping someone on here might be able to provide some info or personal experience with this. Does anyone know or have experience with just doing chemo and no removal of the skin tumors? I will keep everyone updated on the results of Monday as well but any info would be greatly appreciated.

As a side note (not saying this is related but it is a very odd coincidence so I just want to share) Dozer had just gotten the rattlesnake vaccine a few days before the first ones popped up. I know this is not listed as a side effect BUT he had gone two years with nothing and then this. Plus, our other dog, who is one, also received the vaccine and has developed a bump at the injection site. We are monitoring it as well but it appears to finally be shrinking…very slowly. Rattlesnakes are very prominent where we live and we do a lot of mountain hiking with our dogs which is the only reason I decided to get it. I am currently researching this vaccine extensively and trying to find out as much as I can. I am not saying this is the cause but if it is a potential side affect people should know this ahead of time.

Thanks for taking the time to read this. Sorry it was so lengthy.
- Shannon

Last edited by Skeebs637; 10-27-2017 at 11:39 AM.
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Old 10-27-2017, 03:22 PM
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Hoping for the best, keep us updated.
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Old 11-17-2017, 04:33 PM
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Hi Everyone,

Wanted to give an update on my baby boy. We took Dozer in on Monday, October 30th, and as we had suspected surgery was not an option. Due to the number of lumps and the obvious signs that the cancer was in his lymph node (left neck) the specialist felt that chemo was his best option. This is a terminal cancer but treatment and management can prolong his life and since he is for the most part 100% himself right now, beside the lumps/tumors, we decided to go ahead with the treatment. He is only 6 years old and responded extremely well to his chemo treatments two years ago so we are hopeful. The vet did say that the average lifespan after diagnosis is 3-6 months but that is just an average. They have seen them live less than that or years past that. She also said that the cancer he had before was very aggressive and only a small percent of dogs live past the one year mark. We made it to two! It all depends on how the dog and the cancer respond to the treatments.

We started him on a combination of CCNU and vinblastine chemotherapy (as well as daily prednisone). We also did an ultrasound just to make sure that nothing had metastasized internally before we started all this. He had his first vinblastine treatment that day (October 30th) and within three days we started to see results. His lymph node in his neck had shrunk by 50% as well as many of his tumors. By a weeks’ time some of the tumors were almost impossible to find. Fast forward to two weeks out and the lump in his neck is pretty much back to normal. You can feel the lump if you really try and search for it but just looking at him you cannot see anything. He only has a few skin tumors that you can find easily but they are pretty flat for the most part and none of them are “angry” at this point. He had his first CCNU treatment this last Monday (November 13th) and so far so good. He is still his happy self and running around like a maniac. He does have the normal side effects that can be suspected because of all the meds (which we experienced last time he was sick) but nothing major. He is extra thirsty and hungry all the time, has lost some weight but that should only be temporary till he adjust to the prednisone, and has those awful chemo farts. Lol. He thinks he is being spoiled with all the treats (pill disguises) he is getting too. In addition to the above, he is also getting daily Benadryl, Omeprazole, antibiotics (Baytril), and Denamarin (to protect his liver). He was prescribed a few as needed ones for nausea and diarrhea but so far we haven’t needed them. I also have been giving him some Turmeric paste that I made up for him. I figure it can’t hurt and I also started giving it to my other dogs too because it has a lot of benefits in general.

I know eventually the treatment will stop working but for all we know that could be months from now (praying for years), but we will take what we can get. He is a fighter and until he tells me otherwise we will keep on fighting.

Oh and thank goodness for pet insurance!

Last edited by Skeebs637; 11-17-2017 at 04:34 PM. Reason: spacing
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