Reaction to Comfortis???

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Reaction to Comfortis???

This is a discussion on Reaction to Comfortis??? within the Dog Health forums, part of the Keeping and Caring for Dogs category; I recently gave my 11 month old Husky/Lab mix Comfortis. (I believe it was last Thursday night, so approximately 4-5 days ago). The next day ...

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Old 12-14-2009, 05:22 PM
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Reaction to Comfortis???

I recently gave my 11 month old Husky/Lab mix Comfortis. (I believe it was last Thursday night, so approximately 4-5 days ago).

The next day or two, he began losing patches of hair on his back legs, near the tail. He hasn't lost if down to the skin yet, but the hair is getting very thin.

I have been unable to find anything online about hair loss using Comfortis, but I didn't know if anyone else had experienced this or has a suggestion on what the problem might be. (The skin doesn't appear flaky or inflamed where the hair is falling out.)

Thanks.
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Old 12-14-2009, 05:53 PM
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Welcome
I've actually never heard of it but looked it up for you Comfortis.com - Home and I can see it's a flea medication -is that correct?

Did your vet prescribe or dose this out for you? Or did you order it online? Or did you just purchase and give to the dog?


NEVER MIND -
Flush that drug now!!!


COMFORTIS® and ivermectin interaction Safety Warning Notification

It's been recalled for causing adverse reactions in dogs. I believe/gather from the info that it's ivermectin-a wonderful dewormer for horses and rabbits. And it's NOT OK to give to dogs. This is strait from the FDA website linked above

COMFORTIS® and ivermectin interaction Safety Warning Notification

June 24, 2008
Today the U.S. Food and Drug Administration (FDA) Center for Veterinary Medicine (CVM) is announcing that it has received reports of adverse reactions in dogs receiving the drug Comfortis® (spinosad) concurrently with high, extra-label doses of the drug ivermectin. The clinical signs of these adverse reactions are consistent with ivermectin toxicity.
Comfortis® (spinosad), manufactured by Elanco Animal Health, a division of Eli Lilly and Company, is a monthly oral, chewable tablet used for the prevention and treatment of flea infestations on dogs. Veterinarians who use high, extra-label doses of ivermectin to treat dogs with non-responsive demodectic mange and other conditions should be aware that some dogs have developed signs of ivermectin toxicity when ivermectin is used concurrently with Comfortis® (spinosad).
CVM and Elanco Animal Health are advising veterinarians that dogs receiving extra-label doses of ivermectin should not receive concurrent treatment with Comfortis® (spinosad).
CVM is working with Elanco Animal Health as they address this issue. Additional information regarding this safety warning can be obtained on the Elanco Animal Health website.
Lilly Companion Animal Health Technical Bulletin: Spinosad and the Extra-Label Use of High Dose Ivermectin for the Treatment of Generalized Demodicosis in Dogs.



Please respond so I know you got this message about it not being OK!!
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Old 12-14-2009, 05:58 PM
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Yeah, but this recall is a year ago and only applies when the dog receives ivermectin as well.

The vet just gave it to me. I think its supposed to be prescribed though, so I may need to look into that.
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Old 12-14-2009, 06:09 PM
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Tasha takes this, she hasn't had a single problem. That's not the same for all dogs though. I'd call the vet if I were you.

Welcome to the forum by the way!
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Old 12-14-2009, 06:13 PM
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Personally, if I wouldn't give my dog anything that has EVER been recalled if there were another option. If is a flea medication you have many many options that you use. Maybe look into something else.
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Old 12-14-2009, 06:14 PM
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I've tried both Frontline and Advantix and neither has worked. My sister uses Comfortis for hers and didn't have any problems so I thought I'd give it a try.

But if it is causing the hair loss I'll have to look into it some more.
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Old 12-14-2009, 06:21 PM
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What do you use for Heartworm prevention?

We are switching to Sentinel. It is expensive but it prevents heartworms, adult roundworms, adult hookworms, whipworms, AND prevents the development of flea eggs.

If you are using HeartGuard which is about $51 for 6 months and Frontline is $85 for 6 months. Switching to Sentinel which is about $100 for 6 months is actually cheaper (which I just realized when I was looking up the price).
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Old 12-14-2009, 06:42 PM
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BAH sorry !! I just skimmed it-Sorry for the alarm-I was having a heart attack. Yes the recall was a year ago-but it shouldn't be given with ivermectin...in fact from what I've read ivermectin should never be given.

*calms down* Sorry for the false alarm-I feel stoopid now.

OK since you got it from a vet-can you phone the vet and see what he/she says? Honestly I think it would be hard to tell if the hairloss is from the drug or severe flea infection (perhaps mites as well?)

Here's the FDA studies on comfortis http://www.fda.gov/downloads/AnimalV.../ucm062334.pdf the only adverse reactions in all four studies were vomiting.

I think best is to talk to your vet, and discontinue using it until then. My parent's dog is having an adverse reaction to her new glucosamine and it's ok for most dogs so it can certainly be a bad reaction or just the fleas-or even something else?
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Old 12-14-2009, 06:53 PM
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I did call the vet and they said that sometimes if the dog has a bad infestation when the Comfortis is administered that sometimes the fleas dying will actually agitate the dog. I just wanted to see if anyone else had experienced this.

They also said if it continues/worsens to call them. It seems to mainly be the undercoat that my dog is losing.
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Old 12-14-2009, 06:55 PM
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Quote:
I did call the vet and they said that sometimes if the dog has a bad infestation when the Comfortis is administered that sometimes the fleas dying will actually agitate the dog. I just wanted to see if anyone else had experienced this.
Well you didn't mention that-in fact all you mentioned was searching online- so that's why we didn't know.
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