I've actually never heard of it but looked it up for you Comfortis.com - Home
and I can see it's a flea medication -is that correct?
Did your vet prescribe or dose this out for you? Or did you order it online? Or did you just purchase and give to the dog? NEVER MIND - Flush that drug now!!! COMFORTIS® and ivermectin interaction Safety Warning Notification
It's been recalled for causing adverse reactions in dogs. I believe/gather from the info that it's ivermectin-a wonderful dewormer for horses and rabbits. And it's NOT OK to give to dogs. This is strait from the FDA website linked above COMFORTIS® and ivermectin interaction Safety Warning Notification
June 24, 2008
Today the U.S. Food and Drug Administration (FDA) Center for Veterinary Medicine (CVM) is announcing that it has received reports of adverse reactions in dogs receiving the drug Comfortis® (spinosad) concurrently with high, extra-label doses of the drug ivermectin. The clinical signs of these adverse reactions are consistent with ivermectin toxicity.
Comfortis® (spinosad), manufactured by Elanco Animal Health, a division of Eli Lilly and Company, is a monthly oral, chewable tablet used for the prevention and treatment of flea infestations on dogs. Veterinarians who use high, extra-label doses of ivermectin to treat dogs with non-responsive demodectic mange and other conditions should be aware that some dogs have developed signs of ivermectin toxicity when ivermectin is used concurrently with Comfortis® (spinosad).
CVM and Elanco Animal Health are advising veterinarians that dogs receiving extra-label doses of ivermectin should not receive concurrent treatment with Comfortis® (spinosad).
CVM is working with Elanco Animal Health as they address this issue. Additional information regarding this safety warning can be obtained on the Elanco Animal Health website.
Lilly Companion Animal Health Technical Bulletin: Spinosad and the Extra-Label Use of High Dose Ivermectin for the Treatment of Generalized Demodicosis in Dogs. Please respond so I know you got this message about it not being OK!!